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The Science Behind NIMNI™ Technology
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Collagen is the essential protein that gives your skin its firmness, elasticity, and smooth, youthful-looking appearance. But as we age, collagen naturally declines. Factors like UV exposure, stress, pollution, and even lack of sleep accelerate the breakdown of existing collagen and slow your ability to rebuild it.
HydroPeptide has spent more than two decades studying this process. The result is NIMNI™ Technology—a patented collagen-support complex created in partnership with world-renowned collagen researcher Dr. Marcel Nimni, who helped pioneer the discovery of Type II collagen. This innovation is the foundation behind both Nimni Day Cream and the newly renamed Collagen ReActivate PM (formerly Nimni Cream).
This technology is designed to create the optimal conditions for healthy collagen production—and the results speak for themselves.
How NIMNI™ Technology Works
NIMNI™ Technology is a proprietary blend of amino acids and antioxidants that mimics the environment your skin naturally needs to produce abundant, healthy collagen. Unlike surface-level moisturizers, these ingredients penetrate deeply using small, low–molecular-weight molecules and an organic penetrant to support collagen at the source.
Here’s what makes it so powerful:
1. It Stimulates Collagen Production
NIMNI™ Technology reawakens fibroblast activity—the cells responsible for building collagen.
It signals pathways that activate collagen-supporting genes, helping your skin rebuild what time has worn down.
2. It Supports Healthy, Abundant Collagen
Amino acids (at levels found naturally in the body) feed the skin the exact nutrients it needs to sustain ongoing collagen synthesis. These essential building blocks help maintain firmness over time.
3. It Shields Collagen From Breakdown
The antioxidant blend helps protect collagen from environmental and lifestyle-driven damage while supporting the skin’s natural repair processes.
This helps keep collagen stronger, more stable, and more resilient.
Clinical research shows NIMNI™ Technology can increase collagen synthesis by 200% at 90 hours after application.
How Collagen ReActivate PM Uses NIMNI™ Technology
The bestselling Collagen ReActivate PM Lifting Treatment Moisturizer + Retinol takes the power of NIMNI™ Technology and pairs it with targeted nighttime actives to optimize your skin’s repair cycle.
In addition to the patented complex, the PM formula includes:
- Time-release retinol (0.25%) to support cellular turnover and improve texture
- Biomimetic peptides (SYN®-TC and Neodermyl®) to help improve firmness and elasticity
- Antioxidants (Vitamin C and Ellagi-C™) to brighten and protect the skin
A luxurious, nourishing cream texture designed for overnight regeneration
This combination works while you sleep—when your body is naturally in its most restorative state—to visibly lift, firm, and revitalize the skin.
Nimni Day vs. Collagen ReActivate PM: What’s the Difference?
Both formulas are powered by NIMNI™ Technology, but they serve different purposes depending on the time of day:
Designed for daytime collagen support.
It features a targeted antioxidant blend that helps protect skin from environmental stressors and reduce inflammation—two major contributors to collagen degradation.
It maintains and shields collagen throughout the day.
A nighttime formula designed to build and restore collagen.
It pairs NIMNI™ Technology with time-release retinol and regenerative peptides to enhance renewal while you sleep, when your skin’s repair processes peak.
It strengthens, replenishes, and rebuilds collagen overnight.
Together, they create a powerful 24-hour collagen-support system.
Clean, Science-Forward Formulas You Can Trust
Like all HydroPeptide products, both Nimni Day and Collagen ReActivate PM are free of parabens, phthalates, sulfates, genotoxins, and harmful fragrance. Both are vegan, gluten-free, cruelty-free, and formulated with a skin-healthy pH.
HydroPeptide continues to redefine what’s possible in collagen regeneration through clinically validated peptide science and innovations rooted in decades of research.
